Dystrogen Therapeutics is a clinical-stage life sciences company committed to developing personalized therapies for rare genetic diseases. The company focus on treating patients with rare diseases such as Duchenne muscular dystrophy.
The company was founded based on the pioneering work on chimeric cells therapy for transplantation tolerance, developed by Professor Maria Siemionow MD, PhD, a world renowned scientist and surgeon who led a team of surgeons that performed the first near-total face transplantation in the United States. Our technologies are developed in collaboration with the University of Illinois.
At the conference was presented the data from our pre-clinical studies related to systemic delivery of dystrophin expressing chimeric cells “DEC” and how they circumvent the immune response and improve a number of functional characteristics. The new results confirm the feasibility and efficacy of chimeric cell therapy and represent a novel satellite cell-based approach for the treatment of DMD.
Conference poster: Systemically delivering dystrophin expressing chimeric (DEC) cells circumvents an immune response and improves various functional characteristics.(pdf)